Description

The GJB2 gene encodes a member of the gap junction protein family. Gap junctions are large-diameter channels made up of 2 hemichannels–each composed of 6 connexin subunits–on opposing membranes that join through hydrophobic interactions and form an aqueous pore between the cytoplasm of 2 adjacent cells. GJB2 is a gap junction subunit expressed in the developing cortex (Elias et al., 2007).

External Information

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