Description

The TSC2 gene encodes the tuberin protein, whose function is not fully understood. Within cells, tuberin interacts with a protein called hamartin, which is produced from the TSC1 gene. TSC1 and TSC2 are considered tumour suppressor gene and control various cell functions, including cell growth and differentiation during embryogenesis, protein synthesis and autophagy. Hamartin and tuberin carry out their tumor suppressor function by interacting with and regulating a wide variety of other proteins (Zhang et al., 2014).

External Information

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